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in the research, development and commercialization of prescription ophthalmic pharmaceuticals. Alimera Sciences Limited, a wholly owned subsidiary of Alimera, is headquarters of Alimera's European operations in London. Presently Alimera is focused on diseases affecting the back of the eye, or retina. Such forward looking statements are based on current expectations and involve inherent risks and uncertainties, including factors that could delay, divert or change any of them, and could cause actual results to differ materially from those projected in its forward looking statements. In addition to the risks described above and in Alimera's Annual Report on Form 10 K, Quarterly Reports on Form 10 Q, Current Reports on Form 8 K and other filings with the SEC, other unknown or unpredictable factors also could affect Alimera's results. There can be no assurance that the actual results or developments anticipated by Alimera will be realized or, even if substantially realized, that they will have the expected consequences to, or effects on, Alimera. Therefore, no assurance can be given that the outcomes stated in such forward looking statements and estimates will be achieved.
All forward looking statements contained in this press release are expressly qualified by the cautionary statements contained or referred to herein. Alimera cautions investors not to rely too heavily on the forward looking statements Alimera makes or that are made on its behalf. These forward looking statements speak only as of the date of this press release (unless another date is indicated). Alimera undertakes no obligation, and specifically declines any obligation, to publicly update or revise any such forward looking statements, whether as a result of new information, future events or otherwise.
About FAME Safety
Study (ETDRS) eye chart of 15 letters or more. At the completion of the 36 month study, 34 percent had achieved the same result. This effect was highly statistically significant as compared to the sham control group, which received laser and other intravitreally administered therapies.
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ILUVIEN is Alimera's sustained release intravitreal implant that delivers sub microgram levels of fluocinolone acetonide (FAc) for up to 36 months for the treatment of chronic DME. The clinical trial data showed that in patients with chronic DME at month 30, after receiving the ILUVIEN implant, 38 percent of patients experienced an improvement from baseline in their best corrected visual acuity on the Early Treatment of Diabetic Retinopathy Gucci Belts On Sale
For investor inquiries:John Mills, ICR
threat of blindness."ILUVIEN (190 micrograms fluocinolone acetonide intravitreal implant in applicator) is a sustained release intravitreal implant used to treat patients with chronic DME considered insufficiently responsive to available therapies. Each ILUVIEN implant provides a therapeutic effect of up to 36 months by delivering sustained sub microgram levels of fluocinolone acetonide (FAc). ILUVIEN is injected in the back of the patient's eye to a position that takes advantage of the eye's natural fluid dynamics. The applicator employs a 25 gauge needle, which allows for a self sealing wound. In Alimera's FAME Study, the most frequently reported adverse drug reactions included cataract operation, cataract and increased ocular pressure.
"As ophthalmologists, we've been limited Louis Vuitton Knot Belt in our ability to provide relief for chronic diabetic macular edema patients when existing therapies have stopped working," said Jos Maria Ruiz Moreno, professor of Ophthalmology, University of Castilla La Mancha. "With its approval, ILUVIEN covers an important gap in the range of treatment options for chronic diabetic macular edema, and it becomes a source of hope for patients who face the Hermes Belt Double H
Alimera Sciences, Inc., based in Alpharetta, Georgia, is a biopharmaceutical company that specializes Louis Vuitton Belt For Men Price
DME, the primary cause of vision loss associated with diabetic retinopathy, is a disease affecting the macula, the part of the retina responsible for central vision. When the blood vessel leakage of diabetic retinopathy causes swelling in the macula, the condition has progressed to DME. The onset of DME is painless and may go undetected by the patient until it manifests with the blurring of central vision or acute vision loss. The severity of this blurring may range from mild to profound loss of vision. As the population of people with diabetes increases, it is anticipated that the annual incidence of diagnosed DME will increase.
Safety was assessed among those patients treated with ILUVIEN who were in the subgroup of patients with DME for three years or more and were considered to have chronic DME. Intraocular pressure (IOP) increases to 30 millimeters of mercury (mmHg) or greater at any time point were seen in 12.7% of these patients by month 36, compared to 18.4% in the full ILUVIEN treated patient population. By month 36, 3.6% of these patients had undergone an incisional surgical procedure to reduce elevated IOP, compared to 4.8% in the full patient population. The incidence of cataracts among patients with a natural lens in their eye at the start of the study was 84.1% at month 36, with 87.3% undergoing a cataract operation, compared to 81.7% and 80.0%, respectively, in the full patient population.
"With our European management team now on board, we are looking forward to the initial commercial launch of ILUVIEN in Germany, expected during the first quarter of 2013.
About Alimera Sciences, Inc.
Alimera Sciences ILUVIEN0174 Receives Marketing Authorization in Spain for the Treatment of Chronic Diabetic Macular Edema
Alimera Sciences (ALIM) Signs Agreement With Quintiles for European Commercial Launch of ILUVIEN Stryker Corporation (SYK) Buys Trauson, a China Orthopedic Company, for $764 Million
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